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Gabapentin is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA), even though it does not bind to GABA receptors directly. The medication was approved by the U.S. Food and Drug Administration (FDA) in 1993 for the treatment of epilepsy and has broadened its indication over the years. Today, healthcare professionals prescribe gabapentin for neuropathic pain, restless legs syndrome (RLS), and as an adjunctive therapy for certain psychiatric conditions.
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