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Tapentadol is a centrally acting opioid analgesic used for managing moderate to severe pain. It works through two mechanisms: it acts as a mu-opioid receptor agonist and also inhibits the reuptake of norepinephrine, which enhances pain relief. Tapentadol is marketed under the brand name Nucynta, among others, and is typically prescribed for conditions like chronic pain, including neuropathic pain, or acute pain following surgery or injury. It is available in both immediate-release (IR) and extended-release (ER) formulations.