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Tapentadol is a prescription opioid pain reliever used to treat moderate to severe pain. It acts both as an opioid receptor agonist (like traditional opioids) and as a norepinephrine reuptake inhibitor, which helps modulate the body's pain response. Due to its dual mechanism of action, tapentadol is sometimes preferred over other opioids because it may offer pain relief with potentially fewer gastrointestinal side effects, such as constipation. Tapentadol is available in both immediate-release and extended-release forms, with brand names like Nucynta for the immediate-release version.