pancreatic cancer with special focus on topical issues and surgical techniques pdf ifeu

Click to download:

==> pancreatic cancer with special focus on topical issues and surgical techniques pdf <==

Pancreatic cancer is an aggressive malignancy originating from the tissues of the pancreas, often characterized by poor prognosis due to late-stage detection. This form of cancer can manifest in various types, with pancreatic ductal adenocarcinoma being the most common and lethal. It presents significant challenges in diagnosis and treatment due to the pancreas' deep anatomical location and the absence of early symptoms. A critical focus in the management of pancreatic cancer lies in the improvement of surgical techniques, which remains the only potential curative approach for localized disease. The standard surgery, known as the Whipple procedure (pancreaticoduodenectomy), involves removing the head of the pancreas, part of the small intestine, bile duct, and sometimes portions of the stomach. Advancements in minimally invasive surgeries, including laparoscopic and robotic-assisted techniques, have been a topical issue, aiming to reduce recovery time and complications while improving precision. Additionally, neoadjuvant therapies (chemotherapy and radiation before surgery) are gaining attention, particularly for borderline resectable tumors, to shrink the tumor size and improve surgical outcomes. Another pressing issue is the development of effective screening methods and biomarkers for early detection, as most pancreatic cancers are diagnosed at an advanced stage when curative surgery is no longer an option. Immunotherapy, targeted therapies, and personalized medicine also represent critical areas of research, though their application in pancreatic cancer is still in early stages compared to other cancers.