mechanobiology from molecular sensing to disease pdf jfau

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==> mechanobiology from molecular sensing to disease pdf <==

Mechanobiology is an interdisciplinary field that explores how mechanical forces and properties influence biological processes at the molecular level and contribute to various diseases. It delves into the mechanisms by which cells sense and respond to physical stimuli, such as tension, compression, and shear stress, thereby affecting their behavior, structure, and function. This area of study has significant implications for understanding cellular processes like differentiation, migration, and proliferation. For instance, aberrations in mechanosensing can lead to conditions like cancer, fibrosis, and cardiovascular diseases, where the mechanical environment plays a crucial role in disease progression. By investigating the interplay between mechanical forces and biological responses, researchers aim to develop innovative therapeutic strategies and biomaterials that can mimic or alter mechanical signals to promote healing or prevent disease. Ultimately, the insights gained from mechanobiology could revolutionize approaches to tissue engineering and regenerative medicine, offering hope for more effective treatments and better patient outcomes.