c type lectins in immune homeostasis current topics in microbiology and immunology book 429 pdf wgoy

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==> c type lectins in immune homeostasis current topics in microbiology and immunology book 429 pdf <==

C-type lectins are a diverse group of carbohydrate-binding proteins that play a crucial role in immune homeostasis by recognizing and binding specific carbohydrate structures on pathogens and host cells. They are characterized by their reliance on calcium ions for binding, which distinguishes them from other lectin types. In the context of immune function, C-type lectins can act as pattern recognition receptors (PRRs) that initiate innate immune responses upon detecting pathogen-associated molecular patterns (PAMPs), such as those found on fungi, bacteria, and viruses. Their activation leads to various immune responses, including phagocytosis, cytokine production, and the modulation of adaptive immunity. This is essential for maintaining a balanced immune system, as C-type lectins help distinguish between harmful pathogens and benign entities, preventing overactive immune responses that could lead to autoimmunity or chronic inflammation. The study of C-type lectins has broadened our understanding of immune mechanisms and opened avenues for potential therapeutic interventions in various diseases, including infections and autoimmune disorders. In "Current Topics in Microbiology and Immunology," Book 429, these functions of C-type lectins are explored in depth, highlighting their significance in both innate immunity and overall immune system regulation, emphasizing their role in health and disease. The book provides a comprehensive overview of recent advances in understanding the molecular mechanisms underlying C-type lectin function and their implications in immune-related conditions.