behavioral neurobiology of psychedelic drugs pdf wicj

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==> behavioral neurobiology of psychedelic drugs pdf <==

The behavioral neurobiology of psychedelic drugs involves their intricate interactions with the brain's neural circuits and neurotransmitter systems, particularly serotonin receptors, especially the 5-HT2A receptor. Psychedelics like LSD, psilocybin, and DMT primarily induce altered states of consciousness by modulating serotonergic signaling, leading to profound changes in perception, mood, and cognition. This receptor activation enhances connectivity across different brain regions, promoting a more integrated network activity often referred to as "hyperconnectivity." Such changes can result in visual and auditory hallucinations, altered sense of self, and an increased emotional response. Additionally, psychedelics appear to disrupt the default mode network (DMN), a brain network associated with self-referential thought and the ego, which can lead to experiences of ego dissolution and interconnectedness. Be